Do Mitochondria Supplements Work?

Advanced Mitochondrial Support
Advanced Mitochondrial Support 

Mitochondria are important structures that create energy for cells. To do this, they use broken down foods like fat and sugar as building blocks. Next, they use these things to make useable energy for the cell. After that, the cell stores this energy as adenosine triphosphate, also known as ATP. Finally, cells use the ATP as fuel to do their jobs. Their jobs include supporting their organs and keeping humans alive. However, when mitochondria are not working correctly, problems start. First, one problem is having low levels of energy. Second, another problem is the buildup of harmful things called toxins. As a result, a person can have symptoms. In this article, we will discuss more about mitochondrial supplements  in detail.

mitochondrial supplements
mitochondrial supplements

When mitochondria stop working, diseases happen. This is called this mitochondrial dysfunction. As a result, these diseases cause symptoms. First, some symptoms are mild, like fatigue. Second, some symptoms may be severe, like seizures or stroke. Also, problems can happen in any cell but often happen in the muscles and the brain. In short, this is because these organs need a lot of energy.2 Also, dysfunction may happen with diseases like diabetes and cancer.3 There is no cure for mitochondrial disease. Because of this, treatment is meant to help symptoms. Therefore, mitochondria supplements are used for treatment because they can help improve symptoms for people.

Mitochondria Supplements

There are a few things that mitochondria supplements. First, they can improve cell functioning. Second, they can also decrease symptoms. Poor functioning and symptoms occur when the cell is missing parts. As a result, this stops the cell from doing its job. Therefore, the goal is to give back those missing parts. When this happens, the cells can do their work and stay healthy.2 Mitochondrial supplements are made of things the cell naturally needs. Specifically, carnitine, creatine, coenzyme Q10, alpha-lipoic acid, arginine, and B vitamins are used.3,4 These ingredients are used either alone or together. In general, these supplements can help people feel better.

Supplements are usually taken bymouth. Also, you do not need a doctor’s prescription to buy them. In general,the effectiveness, or how well something works, can vary by person. Also,effectiveness depends on many things. These things are the supplement, thedisease, and the person taking it. Not all supplements are equal. Therefore,they do not always help. Although some supplements are helpful, they can alsobe dangerous. In general, talk with a doctor before starting one of these.Above all, this will give you information on benefits and risks. 2-6

Mitochondrial Support

Mitochondria make energy for thecell. This is the energy that allows us to live. Because of this, mitochondrialsupport is important for human health. Healthy cells have all the things theyneed. In unhealthy cells, however, things are missing. Certain parts of thecell are low or gone. For instance, these missing parts may include vitamins,antioxidants, and other things. When this happens, supplements can replacethese missing parts for the cell. This supports the cell and helps boosthealth. Overall, support from supplements can help the cell work better. 1,2

Mitochondrial Support Supplements

The goal of mitochondrial supportsupplements is to help the cell. In short, supplements act in one of two ways.First, they replace things needed for energy production. Second, they protectthe cell from harm. Treatment with supplements are different for each person.Also, treatment for each disease is different. In general, different peopleneed different support. This will provide each person with the best chance ofsuccess. Therefore, the best supplement is one that helps that person’sdisease. Overall, the use of carnitine, CoQ10, arginine, and vitamins are oftenrecommended. 2-4

Best Mitochondrial Supplements

The best mitochondrial supplementsare different for everyone. In other words, there is not one best choice.Mitochondrial diseases include many problems. So, each type of disease has adifferent problem and needs a certain treatment. Also, each person hasdifferent needs for safety. For example, two people who are given the samemedication may very react differently. Because of this, it is hard to predictwhat will happen for patients. Additionally, most supplements are not wellstudied. Because of this, it is hard to compare them to each other. 6Overall, the best supplements are those that are safe and likely to help aspecific person.

Mitochondrial Supplement Reviews

Mitochondrial supplements are notwell studied. This means that scientists have not spent a lot of time learningabout them. Because of this, it is hard to know how well they work. Individualreviews, also called case reports, give descriptions of one person’sexperience. Most often, case reports are the best information we have. Forexample, case reports show that B-vitamins help with fatigue for some people.This information only tells us howone person reacted but does not show how everyone will react. Overall, we can usemitochondrial supplement reviews to make educated guesses.

Mitochondria Boosters

Mitochondria boosters are asupplement that supports the cell. In other words, they boost the cell’shealth. Specifically, there are two groups of supplements for boostingmitochondria. First, one group works by helping the cell make energy. Second,another group works to protect the cell from harmful toxins.4 As aresult, a person might need one or both types. This will depend on what diseasethey have. For example, creatine and vitamin B2 are both supplements to boostmitochondria. Finally, carnitine also boosts health by fighting harmful thingsin the cell. 2,5

Mitochondrial DysfunctionSupplements

Mitochondrial dysfunction is whathappens when mitochondria are working poorly. Therefore, this causes problemsfor the cell. Also, it causes symptoms for people in general. One side effectof this is the buildup of toxins. For treatment, alpha-lipoic acid (ALA) andCoQ10 are used. These act as antioxidants. In other words, they protect thecell from the dangerous things that build up. In addition, mitochondrialdysfunction supplements including creatine and B vitamins may also help. 3,6In many cases, supplements are safe. However, only take supplements formitochondrial dysfunction in recommended amounts and talk with a doctor beforestarting them.

Mitochondrial Repair Supplements

Mitochondria that are very damagedwill eventually stop working. This causes problems for the cell and may causedeath. When this happens, mitochondrial repair supplements may be used. Thesework by helping to restore correct functioning. Unfortunately, there is littleinformation to prove that they work. However, these supplements are still oftenrecommended. This is because they are usually safe. Specific things likeantioxidants and vitamins may help the cell. They help by replacing those partsthat are missing. Overall, this prevents further damage to the cell. It has notyet been proven that these supplements repair the cell.3

Mitochondria Vitamins

Vitamins are one type of supplement.Mitochondria vitamins provide benefit for some people with mitochondrialdisease. Particularly, vitamins act as cofactors in the cell. This means theyhelp the cell make energy. Furthermore, patients with low vitamin levels willget the most benefit from vitamins. For example, a person who has low vitamin Blevels needs more vitamin B. This vitamin B can be given in the form of asupplement. In addition, some vitamins for healthy mitochondria are vitaminsB1, B2, B3, C, D, and E. In conclusion, these vitamins are helpful for somepeople. 4-6

Mitochondrial Energy Optimizer

Overall, mitochondria make energy ina cell. Also, for a person to stay healthy, they need healthy cells.Consequently, the cells without good health may stop working and die. Thiscauses energy in the body to drop and makes people have bad symptoms.Therefore, mitochondria need to stay functioning at a high level. Amitochondrial energy optimizer is a supplement that boosts energy. Examples ofthese are CoQ10, creatine, and other cofactors.2  In summary, people who want to boost theirmitochondria may consider trying these treatments.

Mitochondrial Formula

There are a lot of supplements onthe market, and these supplements come in many formulations. A formulation is acombination of one or more supplements. Mitochondria cocktails are acombination of these different supplements.6 Also, these ingredientscome in different amounts or doses. Although these variations provide a personwith many choices, they can also be confusing. Overall, it is important to knowthe mitochondrial formulation before taking it. This will prevent you fromtaking something that you did not want. In summary, picking the right formulamay be difficult and is different for everyone.

Mitochondrial Health Supplements

People who suffer from poor healthcan struggle to do their daily activities. Similarly, cells that are in poorhealth cannot work well. Because of this, it is important to maintain orincrease the health of cells. Doing so will keep them performing like they aremeant to. Furthermore, people suffering from these mitochondrial diseases canbenefit from mitochondrial health supplements. In general, supplementrecommendations are going to change by person. This means different things areright for different people. In conclusion, mitochondria health supplements canhelp, but it can be hard to find the best one.2,6

Supplements to Increase Mitochondria

There are two main reasons why poorfunctioning can happen. First, the mitochondria are not working right. Second,there are not enough mitochondria. When this happens, energy drops and cellscan die. There is not a lot of data on this topic. So, this means that it ishard to prove that supplements can raise the total amount of mitochondria thata person has. However, one study has shown that vitamin B3, resveratrol, andarginine may help new mitochondria to grow. Data is still unclear.5In conclusion, supplements to increase mitochondria can be tried if a doctorbelieves they are safe for you.

Mitochondrial ATP Supplement

The energy that a cell uses iscalled ATP. This energy is then used in all the activities we do. Themitochondria are responsible for making this energy. So, the mitochondria areimportant for keeping the cell alive. Targeting ATP production withmitochondrial ATP supplements is one way to help. Specifically, creatine,carnitine, CoQ10 are used by the cell during energy creation.2Therefore, people experiencing poor functioning can benefit from taking thesesupplements. Taking a supplement with these parts in it can help replace whatis missing. As a result, this increases energy in the cell and promotes ATPproduction.2,4

Mitochondria Pills

A pill is a medication or dietaryitem that is taken by mouth.7 Furthermore, the word pill is used toidentify many types of medicines. Some of these items may be okay to take, andsome may not. Just because a supplement is in the shape of a pill, does notmean that it is safe. In fact, supplements are controlled differently thanprescription medications. As a result, you cannot assume all supplements are safefor use. Mitochondria pills refer to many things. Before you take a pill,always know what you are taking. Above all, talking with a doctor will provideguidance on taking pills.4

Mitochondrial Biogenesis Supplements

Biogenesis is the production of anew living thing.8 Similarly, Mitochondrial biogenesis is theproduction of new healthy mitochondria. When mitochondria stop working, cellsdie. When this happens, they need to be replaced. Producing new mitochondria isimportant for people who have low levels of them. A person will struggle tostay healthy if their mitochondria levels are low. For example, mitochondrialbiogenesis supplements containing vitamin B3, arginine, and resveratrol mayhelp these people. 5

Mitochondria Products

Mitochondria products aresupplements. In other words, these are two terms used to describe the cellparts that support cell health. These are generally the things that help thecell make energy or protect the cell. For example, some of these products arevitamins, minerals, and antioxidants. Picking the best product may take time.Some products will work better for certain diseases than others. Also, productswork differently by person and there are many products available on the market.Above all, you should always talk to a doctor when starting a new oral product.2-6


In conclusion, mitochondria make energy for the cell. As a result, a cell cannot survive without its mitochondria. Therefore, when mitochondria stop working or die, the cell suffers. Also, this leads to symptoms such as fatigue and other problems. However, people with these diseases may benefit from mitochondria supplements but can have different results. This is because supplements are not all equal. As a result, some people will have relief from supplements and others will not. Therefore, commonly used supplements are carnitine, creatine, CoQ10, alpha-lipoic acid, and B-vitamins. In general, these supplements are considered safe at recommended amounts. Above all, it is important to talk to a doctor before starting one of these supplements.1-6 


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  1. Gahl W. Mitochondria. National Human Genome Research Institute. Accessed September 13, 2020.
  2. Mitochondrial Myopathy Fact Sheet. National Institute of Neurological Disorders and Stroke. Published March 16, 2020. Accessed September 13, 2020.
  3. Nicolson GL. Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements. Integrative Medicine (Ecinitas). 2014;13(4):35-43.
  4. Understanding Mitochondrial Disease: Treatments & Therapies. United Mitochondrial Disease Foundation. Accessed September 13, 2020.
  5. Kuszak AJ, et al. Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems. Annual Review of Pathology: Mechanisms of Disease. 2018;13:123-191.
  6. Dietary Supplements for Primary Mitochondrial Disorders. National Institutes of Health Office of Dietary Supplements. Published June 3, 2020. Accessed September 13, 2020.
  7. Definition of Pill. Merriam-Webster. Accessed September 18, 2020.
  8. Definition of Biogenesis, Merriam-Webster. Accessed September 18, 2020.

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